Below is a list of feature films that Anthony Mackie has starred in. They are listed in reverse-chronological order, with the most recent ones last. Click on the titles to read more about each project individually.
| 2002 | 8 Mile | Papa Doc |
| 2003 | Crossing (Short) | Cass |
| 2003 | Hollywood Homicide | Killer ‘Joker’ |
| 2004 | Brother to Brother | Perry |
| 2004 | Sucker Free City (TV Movie) | K-Luv |
| 2004 | The Manchurian Candidate | Robert Baker |
| 2004 | She Hate Me | John Henry ‘Jack’ Armstrong |
| 2004 | Haven | Hammer |
| 2004 | Million Dollar Baby | Shawrelle Berry |
| 2005 | The Man | Booty |
| 2006 | Half Nelson | Frank |
| 2006 | Freedomland | Billy Williams |
| 2006 | Heavens Fall | William Lee |
| 2006 | Crossover | Tech |
| 2006 | We Are Marshall | Nate Ruffin |
| 2007 | Ascension Day | Turner |
| 2008 | American Violet | Eddie Porter (uncredited) |
| 2008 | The Hurt Locker | Sergeant JT Sanborn |
| 2008 | Eagle Eye | Major William Bowman |
| 2009 | Notorious | Tupac Shakur |
| 2009 | Desert Flower | Harold Jackson |
| 2010 | Night Catches Us | Marcus Washington |
| 2010 | Louis | Buddy Bolden |
| 2011 | The Adjustment Bureau | Harry Mitchell |
| 2011 | Real Steel | Finn |
| 2011 | 10 Years | Andre |
| 2011 | What’s Your Number? | Tom Piper |
| 2012 | Man on a Ledge | Mike Ackerman |
| 2012 | Abraham Lincoln: Vampire Hunter | Will Johnson |
| 2013 | Gangster Squad | Officer Coleman Harris |
| 2013 | Repentance | Tommy Carter |
| 2013 | The Inevitable Defeat of Mister & Pete | Kris |
| 2013 | Pain & Gain | Adrian Doorbal |
| 2013 | The Fifth Estate | Sam Coulson |
| 2013 | Runner Runner | Agent Shavers |
| 2014 | Captain America: The Winter Soldier | Sam Wilson / Falcon |
| 2014 | Black or White | Jeremiah Jeffers |
| 2014 | Shelter | Tahir |
| 2014 | Playing It Cool | Bryan |
| 2015 | Avengers: Age of Ultron | Sam Wilson / Falcon |
| 2015 | Ant-Man | Sam Wilson / Falcon |
| 2015 | Our Brand Is Crisis | Ben |
| 2015 | Love the Coopers | Officer Williams |
| 2015 | The Night Before | Chris Roberts |
| 2016 | Triple 9 | Marcus Atwood |
| 2016 | Captain America: Civil War | Sam Wilson / Falcon |
| 2016 | All the Way (TV Movie) | Martin Luther King, Jr. |
| 2017 | Detroit | Greene |
| 2017 | Wetlands | – |
| 2018 | Avengers: Infinity War | Sam Wilson / Falcon |
| 2018 | The Hate U Give | King |
| 2019 | Miss Bala | Dave |
| 2019 | Io | Micah |
| 2019 | Avengers: Endgame | Sam Wilson / Falcon |
| 2019 | The Woman in the Window | Ed Fox |
| 2019 | Against All Enemies | Hakim Jamal |
| 2019 | The Banker | Bernard Garrett |
| 2019 | Point Blank | Paul |
| 2019 | Synchronic | – |
| – | The Blue Mauritius | Peter |
| – | Signal HIll | Johnnie Cochran |
| – | Untitled Jesse Owens Biopic | Jesse Owens |